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Rosanna Lauren Arquette (born August 10, 1959) is an American actress, film director, and producer.Arquette was born in New York City, the daughter of Brenda Olivia "Mardi" (née Nowak), an actress, poet, theater operator, activist, acting teacher, and therapist, and Lewis Arquette, an actor and director. Her paternal grandfather was comedian Cliff Arquette. Her mother was Jewish, the daughter of a Holocaust refugee from Poland. Her father was a convert to Islam from Catholicism, and was related to explorer Meriwether Lewis. Her siblings Patricia, Alexis, Richmond, and David Arquette are also actors.
In 1963, Arquette and her family moved to Chicago, where her father managed The Second City theater for several years. When she was eleven years old, her parents moved to a commune in Front Royal, Virginia. Arquette did not do well at school. In 1974, she hitchhiked across the country with three older teenagers, eventually going to San Francisco, where she worked at renaissance and Dickens fairs. Her professional theater debut was May 27, 1977, appearing in the Story Theatre Musical production of Ovid's The Metamorphoses at the Callboard Theatre on Melrose Place in Los Angeles.
Arquette was 19 when she married director/composer Tony Greco; they divorced 2 years later in October 1980.
The song "Rosanna" by Toto was not written about Rosanna Arquette by her then boyfriend and Toto band member Steve Porcaro. It was a joke band members used to make, regarding the coincidence.Arquette has appeared in both television and screen films. In 1982, she earned an Emmy Award nomination for the TV film The Executioner's Song. Arquette's first starring role was in John Sayles's Baby It's You, a highly regarded but little seen film. She starred in Desperately Seeking Susan (1985) alongside pop singer Madonna, for which she won a British Academy Film Awards (BAFTA) for her "supporting" role despite her clearly being the lead. Madonna was breaking out at the time and many feel that while Rosanna's performance was key to the movie's success, Madonna made the movie into a mainstream hit. She had negotiated a deal where she would provide a song for the movie. "Into The Groove" became a huge hit for Madonna as did the movie itself. Following the commercial and critical success of Lawrence Kasdan's Silverado in 1985, and the failure of both After Hours and 8 Million Ways to Die, she quit Hollywood to work in Europe where she acted in Luc Besson's The Big Blue (1988).
In 1989, director Martin Scorsese offered her a part in New York Stories. Other movies of note are Pulp Fiction and the David Cronenberg film, Crash and the Australian film Wendy Cracked a Walnut (1990) (also known as …Almost). In 1990, Arquette appeared on the cover and in a nude pictorial in Playboy's September issue, although she claimed it was without her prior knowledge or consent.
In recent years, Arquette has expanded into directing, including the documentaries Searching for Debra Winger (2002) and All We Are Saying (2005); she also produced both projects.
Arquette appeared in the short running What About Brian as Nicole Varsi and on Showtime's The L Word as Cherie Jaffe.
In 2009, she joined Fit Parent Magazine, founded by Craig Knight, as Editor at Large. Arquette stars in the French thriller The Divide, directed by Xavier GensIn 1987, Arquette's first starring roles were as pregnant teenager Stacy in television film Daddy, boarding school student Zero in Pretty Smart, and the attention-getting Kristen Parker in A Nightmare on Elm Street 3: Dream Warriors. In 1991, she won a CableACE Award for her portrayal of a deaf epileptic in Wildflower. In 1993, she starred in Tony Scott's True Romance. She has since appeared in such critically acclaimed movies as Ed Wood as the "worst ever" film director's eventual wife, Beyond Rangoon, Ethan Frome, Lost Highway, Little Nicky, Stigmata, Bringing Out the Dead, Human Nature, Disney's Holes, and Flirting with Disaster.
In January 2005, she began starring in her first television series, NBC's Medium. Her role as (a fictionalized version of) psychic medium Allison DuBois won her an Emmy Award for Outstanding Lead Actress in 2005, as well as nominations for a Golden Globe in 2005, 2006 and 2007, a SAG Award in 2006 and 2010, and an Emmy Award in 2007. In 2009 NBC cancelled Medium, then CBS picked the show up and it lasted another two seasons. By 2011 she was earning $225,000 per episode for the series. Arquette played the role of Allison DuBois until 2011 when the series was brought to an end. The final episode of Medium aired on January 21, 2011.[Arquette was born in Chicago, Illinois, the daughter of Lewis Arquette, an actor, and Brenda Olivia "Mardi" (née Nowak), an actress, poet, theater operator, activist, acting teacher, and therapist. Arquette's mother was Jewish, the daughter of a Holocaust survivor from Poland. Arquette's father was a convert to Islam from Catholicism, and was related to explorer Meriwether Lewis. Her paternal grandfather was comedian Cliff Arquette, and her siblings are actors Rosanna, Alexis, Richmond, and David Arquette.In April 1995, Arquette married Nicolas Cage (with whom she would later co-star in Bringing Out the Dead in 1999). They separated after nine months, but acted as a couple in public until Cage filed for divorce in February 2000. The divorce petition was withdrawn, but Arquette filed again in November 2000.
Arquette has a son, Enzo (born January 3, 1989), with musician Paul Rossi.
Arquette and actor Thomas Jane became engaged in 2002 and have a daughter, Harlow Olivia Calliope (born 2003). Arquette and Jane subsequently married on June 25, 2006 at the Palazzo Contarini in Venice, Italy. In January 2009, Arquette filed for divorce from Jane on the grounds of irreconcilable differences, but the couple soon reconciled and Arquette requested to abandon the divorce petition on July 9, 2009. However, on August 13, 2010, Jane's representative announced that Arquette and Jane had decided to proceed with a divorce due to “irreconcilable differences.” The divorce was finalized on July 1, 2011. The pair were granted joint custody of their childAfter the Haiti earthquake in 2010, Arquette and childhood friend Rosetta Millington-Getty formed GiveLove, a non-profit organization supporting ecological sanitation and composting, community development projects and housing construction in Haiti. She has also worked with Eracism Foundation, Libby Ross Foundation, The Art of Elysium, and The Heart Truth. Most recently, she is doing a commercial for ABC on behalf of People for the Ethical Treatment of Animals for homeless dogs and cats.
In 1997, after her mother died of breast cancer, Arquette worked to raise awareness about the disease. She has run in the annual Race for the Cure, and in 1999 was the spokesperson for Lee National Denim Day, which raises millions of dollars for breast cancer research and education. In April 2010, she teamed-up with welding students of the Robert Morgan Educational Center, in Miami, Florida, to build shelters in earthquake-ravaged Haiti from 20 used shipping containers.